Native Tiers refers to the characters who are Tier-2 or Tier-3 naturally from the beginning.
These characters already have their Tier-2 passive skill when acquired (Sentry’s Ultimate Skill is unlocked when ranked up to 6★). These characters can be identified by the fact that they have the Tier-2 or Tier-3 badge on the top-left corner of their character icon, despite them not being level 60 nor having full 6 star rank and mastery. They are generally stronger than commonly obtainable characters, but they are not viable for combat until they achieve proper leveling, so don't expect immediate good results after obtaining one.
| Character Portrait | Character Name | Location |
|---|---|---|
 |
Jean Grey | Epic Quest: Rise of The X-Men (Rebirth of The Phoenix) |
 |
Scarlet Witch | World Boss |
| Character Portrait | Character Name | Location |
|---|---|---|
 |
Adam Warlock | Shop |
  |
Cable | World Boss |
  |
Doctor Strange | Epic Quest: Sorcerer Supreme |
| Character Portrait | Character Name | Location |
|---|---|---|
| N/A | N/A | N/A |
| Character Portrait | Character Name | Location |
|---|---|---|
  |
Gladiator | Epic Quest: The Galactic Imperative (Ruler of The Empire) |
  |
Mister Fantastic | Epic Quest: First Family |
  |
Wolverine | Epic Quest: Rise of The X-Men |
| Character Portrait | Character Name | Location |
|---|---|---|
| N/A | N/A | N/A |
| Character Portrait | Character Name | Location |
|---|---|---|
  |
Deadpool | Epic Quest: X-Force |
  |
Quicksilver | World Boss |
| Character Portrait | Character Name | Location |
|---|---|---|
| N/A | N/A | N/A |
| Character Portrait | Character Name | Location |
|---|---|---|
  |
Beta Ray Bill | Epic Quest: The Galactic Imperative |
  |
Odin | Shop |
  |
Sentry | Epic Quest: Dark Reign |
  |
Silver Surfer | Giant Boss Raid |
| Character Portrait | Character Name | Location |
|---|---|---|
| N/A | N/A | N/A |
| Character Portrait | Character Name | Location |
|---|---|---|
  |
Apocalypse | World Boss |
| Character Portrait | Character Name | Location |
|---|---|---|
| N/A | N/A | N/A |
| Character Portrait | Character Name | Location |
|---|---|---|
| N/A | N/A | N/A |
| Character Portrait | Character Name | Location |
|---|---|---|
  |
Proxima Midnight | World Boss |
  |
Supergiant | World Boss |
| Character Portrait | Character Name | Location |
|---|---|---|
  |
Black Dwarf | World Boss |
  |
Corvus Glaive | World Boss |
  |
Doctor Doom | Epic Quest: First Family (Ruler of Latveria) |
  |
Dormammu | Shop |
  |
Ebony Maw | World Boss |
  |
Knull | World Boss Legend |
  |
Molecule Man | Epic Quest: Dark Reign (Shaper of Worlds) |
  |
Thanos | World Boss |
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